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MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype
Resistance to neoadjuvant chemoradiation therapy (CRT) remains a critical barrier to the effective treatment of esophageal adenocarcinoma (EAC). Cancer stem-like cells (CSCs) are a distinct subpopulation of cells implicated in the resistance of tumors to anti-cancer therapy. However, their role in t...
Autores principales: | Lynam-Lennon, Niamh, Heavey, Susan, Sommerville, Gary, Bibby, Becky A.S., Ffrench, Brendan, Quinn, Jennifer, Gasch, Claudia, O’Leary, John J, Gallagher, Michael F, Reynolds, John V, Maher, Stephen G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355274/ https://www.ncbi.nlm.nih.gov/pubmed/28002789 http://dx.doi.org/10.18632/oncotarget.13940 |
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