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Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis
The MC1R gene plays a crucial role in pigmentation synthesis. Loss-of-function MC1R variants, which impair protein function, are associated with red hair color (RHC) phenotype and increased skin cancer risk. Cultured cutaneous cells bearing loss-of-function MC1R variants show a distinct gene express...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355288/ https://www.ncbi.nlm.nih.gov/pubmed/28030792 http://dx.doi.org/10.18632/oncotarget.14140 |