Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

Mitochondria can be involved in regulating cellular stress response to hypoxia and tumor growth, but little is known about that mechanistic relationship. Here, we show that mitochondrial deficiency severely retards tumor xenograft growth with impairing hypoxic induction of HIF-1 transcriptional acti...

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Detalles Bibliográficos
Autores principales: Koido, Masaru, Haga, Naomi, Furuno, Aki, Tsukahara, Satomi, Sakurai, Junko, Tani, Yuri, Sato, Shigeo, Tomida, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355308/
https://www.ncbi.nlm.nih.gov/pubmed/28060746
http://dx.doi.org/10.18632/oncotarget.14415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355308/
https://www.ncbi.nlm.nih.gov/pubmed/28060746
http://dx.doi.org/10.18632/oncotarget.14415

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