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Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy

Surgical resection is a standard component of treatment in the clinical management of patients with glioblastoma multiforme (GBM). However, experimental therapies are rarely investigated in the context of tumor debulking in preclinical models. Here, a surgical debulking GBM xenograft model was devel...

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Detalles Bibliográficos
Autores principales: Zhu, Huaiyang, Leiss, Lina, Yang, Ning, Rygh, Cecilie B., Mitra, Siddhartha S., Cheshier, Samuel H., Weissman, Irving L., Huang, Bin, Miletic, Hrvoje, Bjerkvig, Rolf, Enger, Per Ø., Li, Xingang, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355332/
https://www.ncbi.nlm.nih.gov/pubmed/28076333
http://dx.doi.org/10.18632/oncotarget.14553