Human papillomavirus type 16 E6 suppresses microRNA-23b expression in human cervical cancer cells through DNA methylation of the host gene C9orf3

Oncogenic protein E6 of human papillomavirus type 16 (HPV-16) is believed to involve in the aberrant methylation in cervical cancer as it upregulates DNA methyltransferase 1 (DNMT1) through tumor suppressor p53. In addition, DNA demethylating agent induces the expression of one of the HPV-16 E6 regu...

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Detalles Bibliográficos
Autores principales: Yeung, Chi Lam Au, Tsang, Tsun Yee, Yau, Pak Lun, Kwok, Tim Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355333/
https://www.ncbi.nlm.nih.gov/pubmed/28077801
http://dx.doi.org/10.18632/oncotarget.14555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355333/
https://www.ncbi.nlm.nih.gov/pubmed/28077801
http://dx.doi.org/10.18632/oncotarget.14555

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