Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

Forkhead transcription factor (Foxo3a) is a downstream effector of JNK-induced tumor suppression. However, it is not clear whether the caveolin-1 (CAV1)-mediated JNK/Foxo3a pathway is involved in cancer cell apoptosis. We found that cordycepin upregulates CAV1 expression, which was accompanied by JN...

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Detalles Bibliográficos
Autores principales: Joo, Jong Cheon, Hwang, Jung Hoo, Jo, Eunbi, Kim, Young-Rang, Kim, Dae Joon, Lee, Kyung-Bok, Park, Soo Jung, Jang, Ik-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355338/
https://www.ncbi.nlm.nih.gov/pubmed/28099944
http://dx.doi.org/10.18632/oncotarget.14661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355338/
https://www.ncbi.nlm.nih.gov/pubmed/28099944
http://dx.doi.org/10.18632/oncotarget.14661

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