Cargando…

Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma

Forkhead transcription factor (Foxo3a) is a downstream effector of JNK-induced tumor suppression. However, it is not clear whether the caveolin-1 (CAV1)-mediated JNK/Foxo3a pathway is involved in cancer cell apoptosis. We found that cordycepin upregulates CAV1 expression, which was accompanied by JN...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joo, Jong Cheon, Hwang, Jung Hoo, Jo, Eunbi, Kim, Young-Rang, Kim, Dae Joon, Lee, Kyung-Bok, Park, Soo Jung, Jang, Ik-Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355338/ https://www.ncbi.nlm.nih.gov/pubmed/28099944 http://dx.doi.org/10.18632/oncotarget.14661

Ejemplares similares

Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIP(L) expression
por: Hwang, In-Hu, et al.
Publicado: (2017)

Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway
por: Cui, Zhen Yang, et al.
Publicado: (2018)

Chelidonium majus Induces Apoptosis of Human Ovarian Cancer Cells via ATF3-Mediated Regulation of Foxo3a by Tip60
por: Shen, Lei, et al.
Publicado: (2022)

Houttuynia cordata Thunb Promotes Activation of HIF-1A–FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells
por: Kim, Jung Min, et al.
Publicado: (2016)

Direct Regulation of TLR5 Expression by Caveolin-1
por: Lim, Jae Sung, et al.
Publicado: (2015)

Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells
por: Hwang, In-Hu, et al.
Publicado: (2016)

The Anticancer Properties of Cordycepin and Their Underlying Mechanisms
por: Yoon, So Young, et al.
Publicado: (2018)

Flagellin-dependent TLR5/caveolin-1 as a promising immune activator in immunosenescence
por: Lim, Jae Sung, et al.
Publicado: (2015)

Therapeutic Potential and Biological Applications of Cordycepin and Metabolic Mechanisms in Cordycepin-Producing Fungi
por: Qin, Peng, et al.
Publicado: (2019)

Research Progress on Cordycepin Synthesis and Methods for Enhancement of Cordycepin Production in Cordyceps militaris
por: Wang, Li, et al.
Publicado: (2022)

Cordycepin Induces Apoptosis through JNK-Mediated Caspase Activation in Human OEC-M1 Oral Cancer Cells
por: Tung, Kuo-Lung, et al.
Publicado: (2022)

Quantitative Analyses of the Functional Constituents in SanYangSam and SanYangSanSam
por: Shin, Il-Soo, et al.
Publicado: (2017)

Mechanism of Activation of AMPK by Cordycepin
por: Hawley, Simon A., et al.
Publicado: (2020)

Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling
por: Baek, Minwoo, et al.
Publicado: (2018)

Neutral Lipid Content in Lipid Droplets: Potential Biomarker of Cordycepin Accumulation in Cordycepin-Producing Fungi
por: Qin, Peng, et al.
Publicado: (2019)

Cordyceps mushroom with increased cordycepin content by the cultivation on edible insects
por: Turk, Ayman, et al.
Publicado: (2022)

Cordycepin Accelerates Osteoblast Mineralization and Attenuates Osteoclast Differentiation In Vitro
por: Yu, Su-Bin, et al.
Publicado: (2018)

Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis
por: Liu, Sijia, et al.
Publicado: (2021)

Acute Valproate Exposure Induces Mitochondrial Biogenesis and Autophagy with FOXO3a Modulation in SH-SY5Y Cells
por: Jang, Eun-Hye, et al.
Publicado: (2021)

Development of an efficient method for separation and purification of cordycepin from liquid fermentation of Cordyceps militaris and analysis of cordycepin antitumor activity
por: Liu, Peng-xiao, et al.
Publicado: (2023)

ApoE4 attenuates autophagy via FoxO3a repression in the brain
por: Sohn, Hee-Young, et al.
Publicado: (2021)

The Inhibitory Effect of Cordycepin on the Proliferation of MCF-7 Breast Cancer Cells, and Its Mechanism: An Investigation Using Network Pharmacology-Based Analysis
por: Lee, Dahae, et al.
Publicado: (2019)

Role of Cordycepin and Adenosine on the Phenotypic Switch of Macrophages via Induced Anti-inflammatory Cytokines
por: Shin, Seulmee, et al.
Publicado: (2009)

Cordycepin Suppresses Expression of Diabetes Regulating Genes by Inhibition of Lipopolysaccharide-induced Inflammation in Macrophages
por: Shin, Seulmee, et al.
Publicado: (2009)

Caveolin-1 Scaffolding Domain Peptide Regulates Colon Endothelial Cell Survival through JNK Pathway
por: Fang, Kai, et al.
Publicado: (2020)

Correction: Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIP(L) expression
Publicado: (2018)

Immunohistochemical study of caveolin-1 and -2 in the rat retina
por: Kim, Heechul, et al.
Publicado: (2006)

REP1 inhibits FOXO3-mediated apoptosis to promote cancer cell survival
por: Song, Kwon-Ho, et al.
Publicado: (2017)

Adenosine Deaminase Inhibitory Activity of Medicinal Plants: Boost the Production of Cordycepin in Cordyceps militaris
por: Turk, Ayman, et al.
Publicado: (2023)

A Systematic Review of the Biological Effects of Cordycepin
por: Radhi, Masar, et al.
Publicado: (2021)

Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin
por: Jang, Ik-Soon, et al.
Publicado: (2020)

Overexpression of caveolin-1 attenuates brain edema by inhibiting tight junction degradation
por: Choi, Kang-Ho, et al.
Publicado: (2016)

Silibinin Alleviates Muscle Atrophy Caused by Oxidative Stress Induced by Cisplatin through ERK/FoxO and JNK/FoxO Pathways
por: Chi, Meng-yi, et al.
Publicado: (2022)

The effect of autogenous tooth bone graft material without organic matter and type I collagen treatment on bone regeneration
por: Kim, Min-Gu, et al.
Publicado: (2021)

Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
por: Barthélémy, Catherine, et al.
Publicado: (2004)

Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation
por: Jo, Eunbi, et al.
Publicado: (2020)

Trends in the Immunomodulatory Effects of Cordyceps militaris: Total Extracts, Polysaccharides and Cordycepin
por: Lee, Chun-Ting, et al.
Publicado: (2020)

Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma
por: Suzuoki, M, et al.
Publicado: (2002)

Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom Cordyceps militaris Linn., Ameliorates Age-Related Testicular Dysfunction in Rats
por: Kopalli, Spandana Rajendra, et al.
Publicado: (2019)

Pharmacogenomic Assessment of Outcomes of Pemetrexed-Treated Patients with Adenocarcinoma of the Lung
por: Jung, Minkyu, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4ovu63ij47nu2rct53prqheiu9