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Synthesis and evaluation of anticancer activity of 6-pyrazolinylcoumarin derivatives

A series of novel 6-pyrazolinylcoumarins has been synthesized via multi-step protocol. The synthetic procedure was based on the acetylation of hydroxycoumarins; Fries rearrangement and Claisen–Schmidt condensation; the target 6-[5-aryl-4,5-dihydropyrazol-3-yl]-5-hydroxy-7-methylcoumarins (33–49) wer...

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Detalles Bibliográficos
Autores principales: Garazd, Yana, Garazd, Myroslav, Lesyk, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355548/
https://www.ncbi.nlm.nih.gov/pubmed/28344471
http://dx.doi.org/10.1016/j.jsps.2016.05.005