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Prevalence of UDP-glucuronosyltransferase polymorphisms (UGT1A6∗2, 1A7∗12, 1A8∗3, 1A9∗3, 2B7∗2, and 2B15∗2) in a Saudi population

Glucuronidation is an important phase II pathway responsible for many endogenous substances and drug metabolism. The present work evaluated allele frequencies of certain UDP-glucuronosyl-transferases (UGT 1A6∗2, A7∗12, A8∗3, A9∗3, 2B7∗2, and 2B15∗2) in Saudi Arabians that could provide essential eth...

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Detalles Bibliográficos
Autores principales: Alkharfy, Khalid M., Jan, Basit L., Afzal, Sibtain, Al-Jenoobi, Fahad I., Al-Mohizea, Abdullah M., Al-Muhsen, Saleh, Halwani, Rabih, Parvez, Mohammad K., Al-Dosari, Mohammed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355556/
https://www.ncbi.nlm.nih.gov/pubmed/28344472
http://dx.doi.org/10.1016/j.jsps.2016.05.009