Cargando…

An overview of pharmacodynamic modelling, ligand-binding approach and its application in clinical practice

The study of the magnitude and variation of drug response is defined as pharmacodynamics (PDs). PD models examine plasma concentration and effect relationship. It can predict the archetypal effect ([Formula: see text]) of a drug as a function of the drug concentration ([Formula: see text]) and estim...

Descripción completa

Detalles Bibliográficos
Autores principales: Salahudeen, Mohammed Saji, Nishtala, Prasad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355565/
https://www.ncbi.nlm.nih.gov/pubmed/28344466
http://dx.doi.org/10.1016/j.jsps.2016.07.002