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An overview of pharmacodynamic modelling, ligand-binding approach and its application in clinical practice
The study of the magnitude and variation of drug response is defined as pharmacodynamics (PDs). PD models examine plasma concentration and effect relationship. It can predict the archetypal effect ([Formula: see text]) of a drug as a function of the drug concentration ([Formula: see text]) and estim...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355565/ https://www.ncbi.nlm.nih.gov/pubmed/28344466 http://dx.doi.org/10.1016/j.jsps.2016.07.002 |