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The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block

Type I interferon (IFN) signaling engenders an antiviral state that likely plays an important role in constraining HIV-1 transmission and contributes to defining subsequent AIDS pathogenesis. Type II IFN (IFN-γ) also induces an antiviral state but is often primarily considered to be an immunomodulat...

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Detalles Bibliográficos
Autores principales: Rihn, Suzannah J., Foster, Toshana L., Busnadiego, Idoia, Aziz, Muhamad Afiq, Hughes, Joseph, Neil, Stuart J. D., Wilson, Sam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355616/
https://www.ncbi.nlm.nih.gov/pubmed/28100611
http://dx.doi.org/10.1128/JVI.02254-16