Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B

The truncated mutant form of the charged multivesicular body protein 2B (CHMP2B) is causative for frontotemporal dementia linked to chromosome 3 (FTD3). CHMP2B is a constituent of the endosomal sorting complex required for transport (ESCRT) and, when mutated, disrupts endosome-to-lysosome traffickin...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Schmid, Benjamin, Nikolaisen, Nanett K., Rasmussen, Mikkel A., Aldana, Blanca I., Agger, Mikkel, Calloe, Kirstine, Stummann, Tina C., Larsen, Hjalte M., Nielsen, Troels T., Huang, Jinrong, Xu, Fengping, Liu, Xin, Bolund, Lars, Meyer, Morten, Bak, Lasse K., Waagepetersen, Helle S., Luo, Yonglun, Nielsen, Jørgen E., Holst, Bjørn, Clausen, Christian, Hyttel, Poul, Freude, Kristine K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355623/
https://www.ncbi.nlm.nih.gov/pubmed/28216144
http://dx.doi.org/10.1016/j.stemcr.2017.01.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355623/
https://www.ncbi.nlm.nih.gov/pubmed/28216144
http://dx.doi.org/10.1016/j.stemcr.2017.01.012

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