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Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes

Changes in oocyte quality can have great impact on the developmental potential of early embryos. Here we test whether nuclear genome transfer from a developmentally incompetent to a developmentally competent oocyte can restore developmental potential. Using in vitro oocyte aging as a model system we...

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Detalles Bibliográficos
Autores principales: Yamada, Mitsutoshi, Egli, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355644/
https://www.ncbi.nlm.nih.gov/pubmed/28242217
http://dx.doi.org/10.1016/j.stemcr.2017.01.020