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Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons

Neurons communicate by regulated secretion of chemical signals from synaptic vesicles (SVs) and dense-core vesicles (DCVs). Here, we investigated the maturation of these two secretory pathways in micro-networks of human iPSC-derived neurons. These micro-networks abundantly expressed endogenous SV an...

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Detalles Bibliográficos
Autores principales: Emperador Melero, Javier, Nadadhur, Aishwarya G., Schut, Desiree, Weering, Jan V., Heine, Vivi M., Toonen, Ruud F., Verhage, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355645/
https://www.ncbi.nlm.nih.gov/pubmed/28238793
http://dx.doi.org/10.1016/j.stemcr.2017.01.019