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Inhibition of JNK suppresses autophagy and attenuates insulin resistance in a rat model of nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease, the pathological process of which is complex. Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is associated with the mechanism underlying obesity-induced insulin resistance. Furthermore, the JNK signaling p...

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Detalles Bibliográficos
Autores principales: Yan, Hua, Gao, Yanqiong, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355648/
https://www.ncbi.nlm.nih.gov/pubmed/27909723
http://dx.doi.org/10.3892/mmr.2016.5966