A mutation in β-amyloid precursor protein renders SH-SY5Y cells vulnerable to isoflurane toxicity: The role of inositol 1,4,5-trisphosphate receptors

Isoflurane is a commonly used inhaled anesthetic, which induces apoptosis of SH-SY5Y cells in a dose- and time-dependent manner; however, the underlying mechanisms remain unknown. The authors of the present study hypothesized that a mutation in β-amyloid precursor protein (APP), which is a gene asso...

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Detalles Bibliográficos
Autores principales: Liu, Xiang, Song, Shan, Wang, Qiujun, Yuan, Tianbao, He, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355684/
https://www.ncbi.nlm.nih.gov/pubmed/27841000
http://dx.doi.org/10.3892/mmr.2016.5930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355684/
https://www.ncbi.nlm.nih.gov/pubmed/27841000
http://dx.doi.org/10.3892/mmr.2016.5930

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