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Transforming growth factor-β1 suppresses bone morphogenetic protein-2-induced mesenchymal-epithelial transition in HSC-4 human oral squamous cell carcinoma cells via Smad1/5/9 pathway suppression

Squamous cell carcinoma is the most common cancer in the oral cavity. We previously demonstrated that transforming growth factor-β1 (TGF-β1) promotes the epithelial-mesenchymal transition (EMT) of human oral squamous cell carcinoma (hOSCC) cells; however, it remains to be clarified whether the TGF-β...

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Detalles Bibliográficos
Autores principales: Chiba, Takahiro, Ishisaki, Akira, Kyakumoto, Seiko, Shibata, Toshiyuki, Yamada, Hiroyuki, Kamo, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355686/
https://www.ncbi.nlm.nih.gov/pubmed/28035402
http://dx.doi.org/10.3892/or.2016.5338