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Construction of a novel cell-based assay for the evaluation of anti-EGFR drug efficacy against EGFR mutation

Epidermal growth factor receptor (EGFR) overexpression and EGFR-mediated signaling pathway dysregulation have been observed in tumors from patients with various cancers, especially non-small cell lung cancer. Thus, several anti-EGFR drugs have been developed for cancer therapy. For patients with kno...

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Detalles Bibliográficos
Autores principales: Hoshi, Hirotaka, Hiyama, Gen, Ishikawa, Kosuke, Inageda, Kiyoshi, Fujimoto, Jiro, Wakamatsu, Ai, Togashi, Takushi, Kawamura, Yoshifumi, Takahashi, Nobuhiko, Higa, Arisa, Goshima, Naoki, Semba, Kentaro, Watanabe, Shinya, Takagi, Motoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355725/
https://www.ncbi.nlm.nih.gov/pubmed/27840973
http://dx.doi.org/10.3892/or.2016.5227