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Construction of a novel cell-based assay for the evaluation of anti-EGFR drug efficacy against EGFR mutation
Epidermal growth factor receptor (EGFR) overexpression and EGFR-mediated signaling pathway dysregulation have been observed in tumors from patients with various cancers, especially non-small cell lung cancer. Thus, several anti-EGFR drugs have been developed for cancer therapy. For patients with kno...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355725/ https://www.ncbi.nlm.nih.gov/pubmed/27840973 http://dx.doi.org/10.3892/or.2016.5227 |