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A novel PDGF receptor inhibitor-eluting stent attenuates in-stent neointima formation in a rabbit carotid model
A novel drug-eluting stent (DES) is required to target vascular smooth muscle cells (SMCs) without harming endothelial cells (ECs). Platelet-derived growth factor (PDGF) is critical for the proliferation and migration of SMCs. Sunitinib [a PDGF receptor (PDGFR) tyrosine kinase inhibitor]-eluting ste...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355735/ https://www.ncbi.nlm.nih.gov/pubmed/27922693 http://dx.doi.org/10.3892/mmr.2016.5986 |