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A novel PDGF receptor inhibitor-eluting stent attenuates in-stent neointima formation in a rabbit carotid model

A novel drug-eluting stent (DES) is required to target vascular smooth muscle cells (SMCs) without harming endothelial cells (ECs). Platelet-derived growth factor (PDGF) is critical for the proliferation and migration of SMCs. Sunitinib [a PDGF receptor (PDGFR) tyrosine kinase inhibitor]-eluting ste...

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Detalles Bibliográficos
Autores principales: Huang, Chen, Mei, Haijun, Zhou, Min, Zheng, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355735/
https://www.ncbi.nlm.nih.gov/pubmed/27922693
http://dx.doi.org/10.3892/mmr.2016.5986