Calcineurin/nuclear factor-κB signaling mediates isoflurane-induced hippocampal neuroinflammation and subsequent cognitive impairment in aged rats

It is known that inhaled anesthetics induce neuroinflammation and facilitate postoperative cognitive dysfunction (POCD) in aged individuals; however, the mechanisms by which they mediate these effects remain elusive. Inhalation of the isoflurane anesthetic leads to opening of the mitochondrial perme...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhengqian, Ni, Cheng, Xia, Chun, Jaw, Joey, Wang, Yujie, Cao, Yiyun, Xu, Mao, Guo, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355741/
https://www.ncbi.nlm.nih.gov/pubmed/27909728
http://dx.doi.org/10.3892/mmr.2016.5967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355741/
https://www.ncbi.nlm.nih.gov/pubmed/27909728
http://dx.doi.org/10.3892/mmr.2016.5967

Ejemplares similares