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Calcineurin/nuclear factor-κB signaling mediates isoflurane-induced hippocampal neuroinflammation and subsequent cognitive impairment in aged rats

It is known that inhaled anesthetics induce neuroinflammation and facilitate postoperative cognitive dysfunction (POCD) in aged individuals; however, the mechanisms by which they mediate these effects remain elusive. Inhalation of the isoflurane anesthetic leads to opening of the mitochondrial perme...

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Detalles Bibliográficos
Autores principales:	Li, Zhengqian, Ni, Cheng, Xia, Chun, Jaw, Joey, Wang, Yujie, Cao, Yiyun, Xu, Mao, Guo, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355741/ https://www.ncbi.nlm.nih.gov/pubmed/27909728 http://dx.doi.org/10.3892/mmr.2016.5967

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