Identification of common non-coding variants at 1p22 that are functional for non-syndromic orofacial clefting

Genome-wide association studies (GWAS) do not distinguish between single nucleotide polymorphisms (SNPs) that are causal and those that are merely in linkage-disequilibrium with causal mutations. Here we describe a versatile, functional pipeline and apply it to SNPs at 1p22, a locus identified in se...

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Detalles Bibliográficos
Autores principales: Liu, Huan, Leslie, Elizabeth J., Carlson, Jenna C., Beaty, Terri H., Marazita, Mary L., Lidral, Andrew C., Cornell, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355807/
https://www.ncbi.nlm.nih.gov/pubmed/28287101
http://dx.doi.org/10.1038/ncomms14759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355807/
https://www.ncbi.nlm.nih.gov/pubmed/28287101
http://dx.doi.org/10.1038/ncomms14759

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