Converting disulfide bridges in native peptides to stable methylene thioacetals

Disulfide bridges play a crucial role in defining and rigidifying the three-dimensional structure of peptides. However, disulfides are inherently unstable in reducing environments. Consequently, the development of strategies aiming to circumvent these deficiencies – ideally with little structural di...

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Detalles Bibliográficos
Autores principales: Kourra, C. M. B. K., Cramer, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355835/
https://www.ncbi.nlm.nih.gov/pubmed/28451136
http://dx.doi.org/10.1039/c6sc02285e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355835/
https://www.ncbi.nlm.nih.gov/pubmed/28451136
http://dx.doi.org/10.1039/c6sc02285e

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