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Converting disulfide bridges in native peptides to stable methylene thioacetals
Disulfide bridges play a crucial role in defining and rigidifying the three-dimensional structure of peptides. However, disulfides are inherently unstable in reducing environments. Consequently, the development of strategies aiming to circumvent these deficiencies – ideally with little structural di...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355835/ https://www.ncbi.nlm.nih.gov/pubmed/28451136 http://dx.doi.org/10.1039/c6sc02285e |