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Synergistic efficacy of Bisbenzimidazole and Carbonyl Cyanide 3-Chlorophenylhydrazone combination against MDR bacterial strains

Activation of efflux systems and the formation of biofilm are majorly adapted by microbes to resist antimicrobial agents. PPEF (bisbenzimidazole) targeting topoisomerase IA is observed to be an effective bactericidal agent against both Gram-positive and Gram-negative bacterial strains and thus can b...

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Detalles Bibliográficos
Autores principales: Sinha, Devapriya, Pandey, Stuti, Singh, Raja, Tiwari, Vinod, Sad, Kirti, Tandon, Vibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355889/
https://www.ncbi.nlm.nih.gov/pubmed/28303897
http://dx.doi.org/10.1038/srep44419