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Brønsted acid-mediated cyclization–dehydrosulfonylation/reduction sequences: An easy access to pyrazinoisoquinolines and pyridopyrazines

An efficient and alternative synthetic approach has been developed to prepare various N-(arylethyl)piperazine-2,6-diones from 4-benzenesulfonyliminodiacetic acid and primary amines using carbonyldiimidazole in the presence of a catalytic amount of DMAP at ambient temperature. Piperazine-2,6-diones a...

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Detalles Bibliográficos
Autores principales: Rao, Ramana Sreenivasa, Ramanathan, Chinnasamy Ramaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355893/
https://www.ncbi.nlm.nih.gov/pubmed/28382181
http://dx.doi.org/10.3762/bjoc.13.46