Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) T(reg) cells are a source of tumour-associated T(reg) cells

Th17 and regulatory T (T(reg)) cells are integral in maintaining immune homeostasis and Th17–T(reg) imbalance is associated with inflammatory immunosuppression in cancer. Here we show that Th17 cells are a source of tumour-induced Foxp3(+) cells. In addition to natural (n)T(reg) and induced (i)T(reg...

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Detalles Bibliográficos
Autores principales: Downs-Canner, Stephanie, Berkey, Sara, Delgoffe, Greg M., Edwards, Robert P., Curiel, Tyler, Odunsi, Kunle, Bartlett, David L., Obermajer, Nataša
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355894/
https://www.ncbi.nlm.nih.gov/pubmed/28290453
http://dx.doi.org/10.1038/ncomms14649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355894/
https://www.ncbi.nlm.nih.gov/pubmed/28290453
http://dx.doi.org/10.1038/ncomms14649

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