Directed Evolution of Key Residues in Fluorescent Protein Inverses the Polarity of Voltage Sensitivity in the Genetically Encoded Indicator ArcLight

[Image: see text] Genetically encoded calcium indicators (GECIs) produce unprecedentedly large signals that have enabled routine optical recording of single neuron activity in vivo in rodent brain. Genetically encoded voltage indicators (GEVIs) offer a more direct measure of neuronal electrical stat...

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Detalles Bibliográficos
Autores principales: Platisa, Jelena, Vasan, Ganesh, Yang, Amy, Pieribone, Vincent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355904/
https://www.ncbi.nlm.nih.gov/pubmed/28045247
http://dx.doi.org/10.1021/acschemneuro.6b00234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355904/
https://www.ncbi.nlm.nih.gov/pubmed/28045247
http://dx.doi.org/10.1021/acschemneuro.6b00234

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