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Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature

BACKGROUND: Tumours are diverse ecosystems with persistent heterogeneity in various cancer hallmarks like self-sufficiency of growth factor production for angiogenesis and reprogramming of energy metabolism for aerobic glycolysis. This heterogeneity has consequences for diagnosis, treatment and dise...

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Detalles Bibliográficos
Autores principales: Kaznatcheev, Artem, Vander Velde, Robert, Scott, Jacob G, Basanta, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355932/
https://www.ncbi.nlm.nih.gov/pubmed/28183139
http://dx.doi.org/10.1038/bjc.2017.5