Cargando…
Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature
BACKGROUND: Tumours are diverse ecosystems with persistent heterogeneity in various cancer hallmarks like self-sufficiency of growth factor production for angiogenesis and reprogramming of energy metabolism for aerobic glycolysis. This heterogeneity has consequences for diagnosis, treatment and dise...
Autores principales: | Kaznatcheev, Artem, Vander Velde, Robert, Scott, Jacob G, Basanta, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355932/ https://www.ncbi.nlm.nih.gov/pubmed/28183139 http://dx.doi.org/10.1038/bjc.2017.5 |
Ejemplares similares
-
TNF-alpha and melphalan-based isolated limb perfusion: no evidence supporting the early destruction of tumour vasculature
por: Podleska, L E, et al.
Publicado: (2015) -
Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game
por: Basanta, D, et al.
Publicado: (2012) -
Tumour heterogeneity poses a significant challenge to cancer biomarker research
por: Cyll, Karolina, et al.
Publicado: (2017) -
Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
por: De Smedt, L, et al.
Publicado: (2015) -
DCE-MRI biomarkers of tumour heterogeneity predict CRC liver metastasis shrinkage following bevacizumab and FOLFOX-6
por: O'Connor, J P B, et al.
Publicado: (2011)