Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is characterized by steatosis with lobular inflammation and hepatocyte injury. Pirfenidone (PFD) is an orally bioavailable pyridone derivative that has been clinically used for the treatment of idiopathic pulmonary fibrosis. However, it remains unknown whether PF...

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Detalles Bibliográficos
Autores principales: Komiya, Chikara, Tanaka, Miyako, Tsuchiya, Kyoichiro, Shimazu, Noriko, Mori, Kentaro, Furuke, Shunsaku, Miyachi, Yasutaka, Shiba, Kumiko, Yamaguchi, Shinobu, Ikeda, Kenji, Ochi, Kozue, Nakabayashi, Kazuhiko, Hata, Ken-ichiro, Itoh, Michiko, Suganami, Takayoshi, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355985/
https://www.ncbi.nlm.nih.gov/pubmed/28303974
http://dx.doi.org/10.1038/srep44754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355985/
https://www.ncbi.nlm.nih.gov/pubmed/28303974
http://dx.doi.org/10.1038/srep44754

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