The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling

Two structurally and functionally distinct mammalian TOR complexes control cell growth and metabolism in physiological and pathological contexts including cancer. Upregulated glutaminolysis is part of the metabolic reprogramming occurring in cancer, providing fuels for growth but also liberating amm...

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Detalles Bibliográficos
Autores principales: Merhi, Ahmad, Delrée, Paul, Marini, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355986/
https://www.ncbi.nlm.nih.gov/pubmed/28303961
http://dx.doi.org/10.1038/srep44602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355986/
https://www.ncbi.nlm.nih.gov/pubmed/28303961
http://dx.doi.org/10.1038/srep44602

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