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Alteration of osteoblast arrangement via direct attack by cancer cells: New insights into bone metastasis

Intact bone tissue exhibits a characteristic anisotropic microstructure derived from collagen fiber alignment and the related c-axis orientation of apatite crystals, which govern the mechanical properties of bone tissue. In contrast, tumor-invaded bone exhibits a disorganized, less-aligned microstru...

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Detalles Bibliográficos
Autores principales: Kimura, Yumi, Matsugaki, Aira, Sekita, Aiko, Nakano, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356003/
https://www.ncbi.nlm.nih.gov/pubmed/28303941
http://dx.doi.org/10.1038/srep44824