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Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts

Human mesenchymal stromal/stem cells (MSCs) are multipotent and currently undergoing hundreds of clinical trials for disease treatments. To date, no studies have generated induced MSCs from skin fibroblasts with chemicals or growth factors. Here, we established the first chemical method to convert p...

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Detalles Bibliográficos
Autores principales: Lai, Pei-Lun, Lin, Hsuan, Chen, Shang-Fu, Yang, Shang-Chih, Hung, Kuo-Hsuan, Chang, Ching-Fang, Chang, Hsiang-Yi, Lu, Frank Leigh, Lee, Yi-Hsuan, Liu, Yu-Chuan, Huang, Hsiao-Chun, Lu, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356011/
https://www.ncbi.nlm.nih.gov/pubmed/28303927
http://dx.doi.org/10.1038/srep44534