Cargando…

Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts

Human mesenchymal stromal/stem cells (MSCs) are multipotent and currently undergoing hundreds of clinical trials for disease treatments. To date, no studies have generated induced MSCs from skin fibroblasts with chemicals or growth factors. Here, we established the first chemical method to convert p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Pei-Lun, Lin, Hsuan, Chen, Shang-Fu, Yang, Shang-Chih, Hung, Kuo-Hsuan, Chang, Ching-Fang, Chang, Hsiang-Yi, Lu, Frank Leigh, Lee, Yi-Hsuan, Liu, Yu-Chuan, Huang, Hsiao-Chun, Lu, Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356011/ https://www.ncbi.nlm.nih.gov/pubmed/28303927 http://dx.doi.org/10.1038/srep44534

Ejemplares similares

Relationship between Kidney Stone Disease and Arterial Stiffness in a Taiwanese Population
por: Sun, Zih-Jie, et al.
Publicado: (2020)

TGFβ-1 Induced Cross-Linking of the Extracellular Matrix of Primary Human Dermal Fibroblasts
por: Semkova, Mariya E., et al.
Publicado: (2021)

Glucose-6-phosphate dehydrogenase is indispensable in embryonic development by modulation of epithelial-mesenchymal transition via the NOX/Smad3/miR-200b axis
por: Wu, Yi-Hsuan, et al.
Publicado: (2018)

Temporal Trends in Treatment and Outcomes of Acute Myocardial Infarction in Patients With Chronic Obstructive Pulmonary Disease: A Nationwide Population‐Based Observational Study
por: Su, Tse‐Hsuan, et al.
Publicado: (2017)

Response of Dermal Fibroblasts to Biochemical and Physical Cues in Aligned Polycaprolactone/Silk Fibroin Nanofiber Scaffolds for Application in Tendon Tissue Engineering
por: Chen, Chih-Hao, et al.
Publicado: (2017)

Elimination of undifferentiated human embryonic stem cells by cardiac glycosides
por: Lin, Yu-Tsen, et al.
Publicado: (2017)

Measurement of Deformity at the Craniovertebral Junction: Correlation of Triangular Area and Myelopathy
por: Chang, Chih-Chang, et al.
Publicado: (2022)

β-blockers after acute myocardial infarction in patients with chronic obstructive pulmonary disease: A nationwide population-based observational study
por: Su, Tse-Hsuan, et al.
Publicado: (2019)

Impact of Diabetes Mellitus on Head and Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy
por: Kuo, Hsuan-Chih, et al.
Publicado: (2020)

The canine epiphyseal-derived mesenchymal stem cells are comparable to bone marrow derived-mesenchymal stem cells
por: CHANG, Ya-Pei, et al.
Publicado: (2014)

Identification and Characterization of Glycine- and Arginine-Rich Motifs in Proteins by a Novel GAR Motif Finder Program
por: Wang, Yi-Chun, et al.
Publicado: (2023)

Quiescent and Proliferative Fibroblasts Exhibit Differential p300 HAT Activation through Control of 5-Methoxytryptophan Production
por: Cheng, Huei-Hsuan, et al.
Publicado: (2014)

Surface‐enhanced Raman scattering (SERS) by gold nanoparticle characterizes dermal thickening by collagen in bleomycin‐treated skin ex vivo
por: Huang, Po‐Jung, et al.
Publicado: (2023)

Combined Anterior and Posterior Decompression With Fusion for Cervical Ossification of the Posterior Longitudinal Ligament
por: Kuo, Chao-Hung, et al.
Publicado: (2022)

Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis
por: Lin, Ching-Wen, et al.
Publicado: (2016)

Comparing the Therapeutic Mechanism and Immune Response of Human and Mouse Mesenchymal Stem Cells in Immunocompetent Mice With Acute Liver Failure
por: Wang, Chang-Hung, et al.
Publicado: (2023)

Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan
por: Cheng, Huei-Hsuan, et al.
Publicado: (2016)

Corrigendum: Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis
por: Lin, Ching-Wen, et al.
Publicado: (2017)

Discovery of 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenoxy)-chromen-4-one with Lipid Lowering Effects in Hepatocytes
por: Chang, Yi-Han, et al.
Publicado: (2022)

Comparison of Cortical Bone Trajectory to Pedicle-Based Dynamic Stabilization: An Analysis of 291 Patients
por: Chang, Chih-Chang, et al.
Publicado: (2023)

Nature or nurture: a latent ossification of the posterior longitudinal ligament after atlantoaxial fusion. Illustrative case
por: Tzeng, Shih-Wei, et al.
Publicado: (2022)

Chrysin Attenuates Cell Viability of Human Colorectal Cancer Cells through Autophagy Induction Unlike 5-Fluorouracil/Oxaliplatin
por: Lin, Yueh-Ming, et al.
Publicado: (2018)

Galangin Reverses H(2)O(2)-Induced Dermal Fibroblast Senescence via SIRT1-PGC-1α/Nrf2 Signaling
por: Lee, Jian-Jr, et al.
Publicado: (2022)

Cell Type-Specific Dependency on the PI3K/Akt Signaling Pathway for the Endogenous Epo and VEGF Induction by Baicalein in Neurons versus Astrocytes
por: Sun, Yu-Yo, et al.
Publicado: (2013)

Improving chemical disease relation extraction with rich features and weakly labeled data
por: Peng, Yifan, et al.
Publicado: (2016)

Acute respiratory distress syndrome and acute myocarditis developed in a previously healthy adult with influenza B
por: Chang, Hsu-Liang, et al.
Publicado: (2016)

Development of a Chemical Cocktail That Rescues Mouse Brain Demyelination in a Cuprizone-Induced Model
por: Lai, Pei-Lun, et al.
Publicado: (2022)

Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway
por: Chen, Wei‐Ju, et al.
Publicado: (2022)

Mining chemical patents with an ensemble of open systems
por: Leaman, Robert, et al.
Publicado: (2016)

tmChem: a high performance approach for chemical named entity recognition and normalization
por: Leaman, Robert, et al.
Publicado: (2015)

Addition of one session with a specialist counselor did not increase efficacy of a family physician-led smoking cessation program
por: Chung, Yi-Hsuan, et al.
Publicado: (2018)

Enrichment of SOX2-Positive Cells in BRAF V600E Mutated and Recurrent Ameloblastoma
por: Tseng, Chih-Huang, et al.
Publicado: (2022)

Contemporary Molecular Analyses of Malignant Tumors for Precision Treatment and the Implication in Oral Squamous Cell Carcinoma
por: Chang, Julia Yu Fong, et al.
Publicado: (2021)

Performance of Six Clinical Physiological Scoring Systems in Predicting In-Hospital Mortality in Elderly and Very Elderly Patients with Acute Upper Gastrointestinal Bleeding in Emergency Department
por: Wu, Po-Han, et al.
Publicado: (2023)

Type II Collagen from Cartilage of Acipenser baerii Promotes Wound Healing in Human Dermal Fibroblasts and in Mouse Skin
por: Lai, Ching-Shu, et al.
Publicado: (2020)

Pleural cytokines MIF and MIP-3α as novel biomarkers for complicated parapneumonic effusions and empyema
por: Yang, Chia-Yu, et al.
Publicado: (2021)

Assessment of Prolonged Dengue Virus Infection in Dermal Fibroblasts and Hair-Follicle Dermal Papilla Cells
por: Wei, Kai-Che, et al.
Publicado: (2020)

Using deep learning to identify maturity and 3D distance in pineapple fields
por: Chang, Chia-Ying, et al.
Publicado: (2022)

Chemical Vapor Deposition-Fabricated Manganese-Doped and Potassium-Doped Hexagonal Tungsten Trioxide Nanowires with Enhanced Gas Sensing and Photocatalytic Properties
por: Chen, Pin-Ru, et al.
Publicado: (2022)

One-pot synthesis of poly (3,4-ethylenedioxythiophene)-Pt nanoparticle composite and its application to electrochemical H(2)O(2) sensor
por: Chang, Li-Chi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ggegm4jci3vbuvvr3l52ffu6n0