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Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth

Toll-like receptors (TLRs) are located either on the cell surface or intracellularly in endosomes and their activation normally contributes to the induction of protective immune responses. However, in cancer their activation by endogenous ligands can modulate tumour progression. It is currently unkn...

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Detalles Bibliográficos
Autores principales: Klein, Johanna C., Moses, Katrin, Zelinskyy, Gennadiy, Sody, Simon, Buer, Jan, Lang, Stephan, Helfrich, Iris, Dittmer, Ulf, Kirschning, Carsten J., Brandau, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356072/
https://www.ncbi.nlm.nih.gov/pubmed/28300057
http://dx.doi.org/10.1038/ncomms14600