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Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth
Toll-like receptors (TLRs) are located either on the cell surface or intracellularly in endosomes and their activation normally contributes to the induction of protective immune responses. However, in cancer their activation by endogenous ligands can modulate tumour progression. It is currently unkn...
Autores principales: | Klein, Johanna C., Moses, Katrin, Zelinskyy, Gennadiy, Sody, Simon, Buer, Jan, Lang, Stephan, Helfrich, Iris, Dittmer, Ulf, Kirschning, Carsten J., Brandau, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356072/ https://www.ncbi.nlm.nih.gov/pubmed/28300057 http://dx.doi.org/10.1038/ncomms14600 |
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