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HBV quasispecies composition in Lamivudine-failed chronic hepatitis B patients and its influence on virological response to Tenofovir-based rescue therapy

The present study sought to evaluate the structure of HBV quasispecies in Lamivudine (LMV)-failed chronic hepatitis B (CHB) patients and its impact in defining the subsequent virological responses to Tenofovir (TDF)-based rescue-therapy. By analyzing HBV clones encompassing reverse transcriptase (RT...

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Detalles Bibliográficos
Autores principales: Banerjee, Priyanka, Chakraborty, Abhijit, Mondal, Rajiv Kumar, Khatun, Mousumi, Datta, Somenath, Das, Kausik, Pandit, Pratap, Mukherjee, Souvik, Banerjee, Soma, Ghosh, Saurabh, Chakrabarti, Saikat, Chowdhury, Abhijit, Datta, Simanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356183/
https://www.ncbi.nlm.nih.gov/pubmed/28303969
http://dx.doi.org/10.1038/srep44742