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Vector Integration Sites Identification for Gene-Trap Screening in Mammalian Haploid Cells

Forward genetic screens using retroviral (or transposon) gene-trap vectors in a haploid genome revolutionized the investigation of molecular networks in mammals. However, the sequencing data generated by Phenotypic interrogation followed by Tag sequencing (PhiT-seq) were not well characterized. The...

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Detalles Bibliográficos
Autores principales: Yu, Jian, Ciaudo, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356192/
https://www.ncbi.nlm.nih.gov/pubmed/28303933
http://dx.doi.org/10.1038/srep44736