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Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells
BACKGROUND: Approximately 18–20% of all human breast cancers have overexpressed human epidermal growth factor receptor 2 (HER2). Standard clinical practice is to treat only overexpressed HER2 (HER2+) cancers with targeted anti-HER2 therapies. However, recent analyses of clinical trial data have foun...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356237/ https://www.ncbi.nlm.nih.gov/pubmed/28302091 http://dx.doi.org/10.1186/s12885-017-3181-0 |