Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis

BACKGROUND: CCAAT/enhancer binding protein β (C/EBPβ) is a transcription factor that regulates the expression of important pro-inflammatory genes in microglia. Mice deficient for C/EBPβ show protection against excitotoxic and ischemic CNS damage, but the involvement in this neuroprotective effect of...

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Detalles Bibliográficos
Autores principales: Pulido-Salgado, Marta, Vidal-Taboada, Jose M., Garcia Diaz-Barriga, Gerardo, Serratosa, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals, Josep M., Valledor, Annabel, Solà, Carme, Saura, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356255/
https://www.ncbi.nlm.nih.gov/pubmed/28302135
http://dx.doi.org/10.1186/s12974-017-0834-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356255/
https://www.ncbi.nlm.nih.gov/pubmed/28302135
http://dx.doi.org/10.1186/s12974-017-0834-5

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