Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function

BACKGROUND: HIV-1 Vif interacts with the cellular core-binding factor β (CBFβ) and counteracts the protective roles of certain human APOBEC3 (A3) proteins by targeting them for proteasomal degradation. Previous studies have identified some amino acids important for Vif–CBFβ interactions, and recentl...

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Detalles Bibliográficos
Autores principales: Desimmie, Belete A., Smith, Jessica L., Matsuo, Hiroshi, Hu, Wei-Shau, Pathak, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356271/
https://www.ncbi.nlm.nih.gov/pubmed/28302150
http://dx.doi.org/10.1186/s12977-017-0346-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356271/
https://www.ncbi.nlm.nih.gov/pubmed/28302150
http://dx.doi.org/10.1186/s12977-017-0346-5

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