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Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma
BACKGROUND: The O (6)-methylguanine methyltransferase (MGMT) gene is frequently unmethylated in patients with glioblastoma (GBM), rendering them non-responsive to the standard treatment regime of surgery followed by concurrent radiotherapy (RT) and temozolomide. Here, we investigate the efficacy of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356284/ https://www.ncbi.nlm.nih.gov/pubmed/28314386 http://dx.doi.org/10.1186/s12967-017-1164-1 |