DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas

BACKGROUND: Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In non-trophoblastic cells, however, the expression of...

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Detalles Bibliográficos
Autores principales: Benešová, Martina, Trejbalová, Kateřina, Kovářová, Denisa, Vernerová, Zdenka, Hron, Tomáš, Kučerová, Dana, Hejnar, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://www.ncbi.nlm.nih.gov/pubmed/28302141
http://dx.doi.org/10.1186/s12977-017-0342-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356313/
https://www.ncbi.nlm.nih.gov/pubmed/28302141
http://dx.doi.org/10.1186/s12977-017-0342-9

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