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Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis

BACKGROUND: Axonal damage and loss substantially contribute to the incremental accumulation of clinical disability in progressive multiple sclerosis. Here, we assessed the amount of Wallerian degeneration in brain tissue of multiple sclerosis patients in relation to demyelinating lesion activity and...

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Detalles Bibliográficos
Autores principales: Singh, Shailender, Dallenga, Tobias, Winkler, Anne, Roemer, Shanu, Maruschak, Brigitte, Siebert, Heike, Brück, Wolfgang, Stadelmann, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356322/
https://www.ncbi.nlm.nih.gov/pubmed/28302146
http://dx.doi.org/10.1186/s12974-017-0831-8