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Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis
BACKGROUND: Axonal damage and loss substantially contribute to the incremental accumulation of clinical disability in progressive multiple sclerosis. Here, we assessed the amount of Wallerian degeneration in brain tissue of multiple sclerosis patients in relation to demyelinating lesion activity and...
Autores principales: | Singh, Shailender, Dallenga, Tobias, Winkler, Anne, Roemer, Shanu, Maruschak, Brigitte, Siebert, Heike, Brück, Wolfgang, Stadelmann, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356322/ https://www.ncbi.nlm.nih.gov/pubmed/28302146 http://dx.doi.org/10.1186/s12974-017-0831-8 |
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