Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of enzymes that are typically released from intracellular stores to act on specific extracellular substrates. MMP expression and activity can be increased in a neuronal activity-dependent manner, and further increased in response to tissue in...

Descripción completa

Detalles Bibliográficos
Autores principales: Conant, Katherine, Daniele, Stefano, Bozzelli, P. Lorenzo, Abdi, Tsion, Edwards, Amanda, Szklarczyk, Arek, Olchefske, India, Ottenheimer, David, Maguire-Zeiss, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356362/
https://www.ncbi.nlm.nih.gov/pubmed/28302163
http://dx.doi.org/10.1186/s12974-017-0827-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356362/
https://www.ncbi.nlm.nih.gov/pubmed/28302163
http://dx.doi.org/10.1186/s12974-017-0827-4

Ejemplares similares