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Altered functional resting-state hypothalamic connectivity and abnormal pituitary morphology in children with Prader-Willi syndrome

BACKGROUND: Prader-Willi syndrome (PWS) is a complex neurodevelopmental disorder, characterized by endocrine problems and hyperphagia, indicating hypothalamic-pituitary dysfunction. However, few studies have explored the underlying neurobiology of the hypothalamus and its functional connectivity wit...

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Detalles Bibliográficos
Autores principales: Lukoshe, Akvile, van Dijk, Suzanne E., van den Bosch, Gerbrich E., van der Lugt, Aad, White, Tonya, Hokken-Koelega, Anita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356363/
https://www.ncbi.nlm.nih.gov/pubmed/28331554
http://dx.doi.org/10.1186/s11689-017-9188-7