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Aprepitant for refractory cutaneous T-cell lymphoma-associated pruritus: 4 cases and a review of the literature
BACKGROUND: Aprepitant is an FDA-approved medication for chemotherapy-induced nausea and vomiting. It blocks substance P binding to neurokinin-1; substance P has been implicated in itch pathways both as a local and global mediator. CASE PRESENTATIONS: We report a series of four patients, diagnosed w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356405/ https://www.ncbi.nlm.nih.gov/pubmed/28302100 http://dx.doi.org/10.1186/s12885-017-3194-8 |